Among the pathological conditions of hypersecretion of liquids is Ménière’s disease, which is characterized by symptoms such as auricular fullness, tinnitus (whistling, buzzing, internal pulsations in the ear), dizziness and hearing loss.
It is now almost certain that the symptoms are due to an increase in fluid (endolymph and perilymph) in the inner ear, with a consequent increase in pressure.
The solutions proposed by PIAM for this pathological condition are based on Antisecretory Factor (AF), a protein that modulates the transport of water and ions.
The discovery of Antisecretory Factor dates back to 1984. At that period researchers had observed that this protein was able to inhibit the hypersecretion of liquids inside the intestinal lumen caused by the cholera toxin.
Antisecretory Factor is present in the cells of all tissues but is particularly abundant in the intestinal mucosa. It acts by blocking the chlorine channels which, when excessively activated, cause hypersecretion in the intestinal lumen.
Specific dietary approaches lead to increased levels of Antisecretory Factor and, therefore, to improving the symptoms of the hypersecretion of liquids.
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